Microvascular effects of a mixed meal tolerance test: a model validation study.
Sebastiaan J W van KraaijBoukje C Eveleens MaarseFemke P M HoevenaarsInes WarnkeMarieke L de KamMatthijs MoerlandPim GalPublished in: Clinical physiology and functional imaging (2024)
SDFM, PLM and LSCI LTH endpoints displayed high intra-subject variability and did not detect consistent effects of MMTT. LSCI PORH endpoints displayed the lowest intra-subject variability of all assessed endpoints and were affected by the MMTT on Day 1, but not on Day 84. Further standardization of methods or more robust challenges to affect vascular endpoints may be needed.
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