Network based integrated analysis of phenotype-genotype data for prioritization of candidate symptom genes.

Xing Li Xuezhong ZhouYonghong PengBaoyan Liu Runshun ZhangJingqing HuJian YuCaiyan JiaChangkai Sun

Published in: BioMed research international (2014)

Our study demonstrated that by integrating phenotype-genotype relationships into a complex network framework it provides an effective approach to identify candidate genes of symptoms.

Keyphrases

big data
gene expression
sleep quality
dna methylation
depressive symptoms
network analysis
patient reported
transcription factor
data analysis
genome wide analysis