Impact of Comorbidities and Commonly Used Drugs on Mortality in COPD - Real-World Data from a Primary Care Setting.
Jens EllingsenGunnar JohanssonKjell LarssonKarin LisspersMalinovschi AndreiBjörn StällbergMarcus ThuressonChrister JanssonPublished in: International journal of chronic obstructive pulmonary disease (2020)
This large, retrospective, observational study of Swedish real-world primary care COPD patients indicates that coexisting heart failure, stroke and myocardial infarction were the strongest predictors of death, underscoring the importance of timely recognition and treatment of comorbidities. A decreased risk of death associated with the use of ICS, beta-blockers and ASA, and an increased risk associated with the use of LAMA and NAC, was also found.
Keyphrases
- primary care
- heart failure
- chronic obstructive pulmonary disease
- end stage renal disease
- atrial fibrillation
- lung function
- ejection fraction
- newly diagnosed
- chronic kidney disease
- transcription factor
- prognostic factors
- risk factors
- peritoneal dialysis
- general practice
- type diabetes
- combination therapy
- subarachnoid hemorrhage
- cystic fibrosis
- deep learning