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Inhibitory effects of silodosin on the bladder mechanosensitive afferent activities and their relation with bladder myogenic contractions in male rats with bladder outlet obstruction.

Naoki AizawaDaiji WatanabeHiroshi FukuharaTetsuya FujimuraHaruki KumeYukio HommaYasuhiko Igawa
Published in: Neurourology and urodynamics (2018)
The present results suggest that silodosin inhibits the SAAs of mechanosensitive Aδ- and C-fibers at least partly due to suppressing myogenic bladder contractions in male BOO rats.
Keyphrases
  • spinal cord injury
  • urinary tract
  • skeletal muscle
  • lower urinary tract symptoms
  • benign prostatic hyperplasia
  • signaling pathway