The Association Between Genetic Polymorphisms in Estrogen Receptor Genes and the Risk of Ocular Disease: A Meta-Analysis

Published in: Turkish journal of ophthalmology (2021)

The recessive genotype of ESR2 rs1256031 gene polymorphism had a protective effect against ocular disease, which supports the hypothesis that the estrogen-signaling pathway through ERβ plays a pivotal role in the pathogenesis of ophthalmic disorders.

Keyphrases

estrogen receptor
signaling pathway
epithelial mesenchymal transition
optic nerve
cell proliferation
genome wide identification
muscular dystrophy