Altered prefrontal-striatal theta-band oscillatory dynamics underlie working memory deficits in neuropathic pain rats.

Helder Cardoso-Cruz Inês C Laranjeira Clara Monteiro Vasco Galhardo

Published in: European journal of pain (London, England) (2022)

Selective optogenetic inhibition of prefrontal-striatal microcircuit reverses pain-related working memory deficits but has no significant impact on pain responses. Neuropathic pain underlies an increase of functional connectivity between the nucleus accumbens core area and the prelimbic medial prefrontal cortex mediated by theta-band activity.

Keyphrases

working memory
neuropathic pain
functional connectivity
resting state
prefrontal cortex
spinal cord
spinal cord injury
transcranial direct current stimulation
traumatic brain injury
attention deficit hyperactivity disorder
chronic pain
transcranial magnetic stimulation