Nigrosome 1 imaging in REM sleep behavior disorder and its association with dopaminergic decline.

Thomas R BarberLudovica GriffantiKevin M BradleyDaniel R McGowanChristine LoClare E MackayMichele T HuJohannes C Klein

Published in: Annals of clinical and translational neurology (2019)

Over one quarter of RBD patients have abnormal substantia nigra SWI reminiscent of Parkinson's, which is associated with a greater dopaminergic deficit. This modality may help enrich neuroprotective trials with early converters.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
high resolution
prognostic factors
physical activity
photodynamic therapy