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Arterial Hypertension, Structural Damage of the Brain and Cognitive Test

Augusto VicarioMariano López SuárezAlicia Ruth FernándezJulio EndersGustavo H Cerezo
Published in: Vertex (Buenos Aires, Argentina) (2024)
average age 69.7 ± 10.6 years, 55.7% female). Based on the linear regression analysis, Fazekas scale and cognitive tests were inversely associated. For each grade of increase in Fazekas scale, the clock drawing test (Coef -0.56, CI 95% -1.01 -0.10, p=0.01) and the Mini-mental Status Examination (Coef -0.7, CI 95% -1.27 -0.13, p=0.01) scores decreased. The subcortical atrophy was significantly associated with the clock drawing test (OR 3.29, CI 95% 1.25-8.63; p=0.016). Conclusion: The cognitive tests, particularly the clock drawing test could be used (in the clinical routine practice) as “subrrogate” of the brain structural hypertension-mediated damage.
Keyphrases
  • arterial hypertension
  • white matter
  • oxidative stress
  • blood pressure
  • primary care
  • healthcare
  • resting state
  • mental health
  • clinical practice
  • blood brain barrier
  • neural network