Opening of the Blood-Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models.

Aria SabbaghKevin BeccariaXiaoyang LingAnantha MarisettyMartina OttHillary CarusoEmily BartonLing-Yuan KongDexing FangKhatri LathaDaniel Yang ZhangJun WeiJohn DeGrootMichael A CurranGanesh RaoJian HuCarole DesseauxGuillaume BouchouxMichael Canney Alexandre CarpentierAmy B Heimberger

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

LIPU increases immune therapeutic delivery to the tumor microenvironment with an associated increase in survival and is an emerging technique for enhancing novel therapies in the brain.

Keyphrases

resting state
magnetic resonance imaging
white matter
functional connectivity
cell therapy
free survival
stem cells
bone marrow