Heteromeric formation with βA3 protects the low thermal stability of βB1-L116P.
Jingjie XuYing ZhangJian LiuLidan HuChenqi LuoPanpan YeXiangjun ChenPublished in: The British journal of ophthalmology (2022)
Decreased βB1-crystallin thermal stability in the presence of the cataract-related L116P mutation contributes significantly to congenital cataract formation. Moreover, its formation of heteromers with βA3 protects against the low thermal stability of βB1-L116P.
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