The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism.
Sophia MetzNikolaj T KrarupThomas BryrupJulie StøyEhm A AnderssonChristina ChristoffersenMatt J NevilleMalene R ChristiansenAnna E JonssonDaniel R WitteUlla KampmannLars B NielsenNiklas R JørgensenFredrik KarpeNiels GrarupOluf PedersenTuomas O KilpeläinenTorben HansenPublished in: Journal of the Endocrine Society (2022)
Taken together, our results indicate an association between the Arg82Cys variant and a lower concentration of HDL particles and HDLc, especially in larger HDL subclasses, suggesting a link between nepmucin and HDLc metabolism or maturation.
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