Novel genetic association between obesity, colorectal cancer, and inflammatory bowel disease.

Published in: Journal of diabetes and metabolic disorders (2023)

The rs3184504 variant and the novel haplotype AGCAGT co-occurred in CRC, IBD, obesity, and inflammation. This novel haplotype could potentially be used in genetic panels to identify CRC/IBD susceptibility in obese patients.

Keyphrases

obese patients
weight loss
bariatric surgery
insulin resistance
metabolic syndrome
roux en y gastric bypass
gastric bypass
high fat diet induced
type diabetes
genome wide
weight gain
ulcerative colitis
oxidative stress
copy number
dna methylation
body mass index
adipose tissue
skeletal muscle