The Circulating GRP78/BiP Is a Marker of Metabolic Diseases and Atherosclerosis: Bringing Endoplasmic Reticulum Stress into the Clinical Scenario.

Josefa GironaCèlia Rodríguez-BorjabadDaiana IbarretxeJoan-Carles VallvéRaimon FerréMercedes HerasRicardo Rodríguez-CalvoSandra Guaita-EsteruelasNeus Martínez-MicaeloNúria PlanaLluís Masana

Published in: Journal of clinical medicine (2019)

GRP78/BiP plasma concentrations are increased in patients with both metabolic derangements and subclinical atherosclerosis. GRP78/BiP could be a useful marker of metabolic and cardiovascular risk.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
cardiovascular disease
type diabetes
oxidative stress