Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions.
Pasquale AmbrosinoAntimo PapaAgostino BuonauroMarco MosellaIlenia Lorenza CalcaterraGiorgio Alfredo SpedicatoMauro ManiscalcoMatteo Nicola Dario Di MinnoPublished in: European journal of clinical investigation (2021)
Impaired endothelial function can be documented in HFpEF, with the possibility of a direct association between the severity of diastolic and endothelial dysfunction. Targeting endothelial dysfunction through pharmacological and rehabilitation strategies may represent an attractive therapeutic option.