Increased apolipoprotein E and decreased TNF-α in the cerebrospinal fluid of nondemented APOE-ε4 carriers.
Daimei SasayamaKotaro HattoriYuuki YokotaRyo MatsumuraToshiya TeraishiSumiko YoshidaHiroshi KunugiPublished in: Neuropsychopharmacology reports (2020)
Our findings indicate the possible roles of apoE and TNF-α in the pathogenesis of APOE-ε4-associated Alzheimer's disease.