Depleted polymorphonuclear leukocytes in human metastatic liver reflect an altered immune microenvironment associated with recurrent metastasis.
Fiona HandCathal HarmonLouise A ElliottFrancesco CaiazzaAonghus LavelleDonal MaguireEmir HotiNiamh NolanJustin G GeogheganElizabeth J RyanCliona O'FarrellyPublished in: Cancer immunology, immunotherapy : CII (2018)
The local inflammatory environment may affect both immune cell infiltration and cancer cell migration contributing to recurrence following resection for CRLM.