Mutational profiling and immunohistochemical analysis of a surgical series of ampullary carcinomas.

Mads Rohde HarthimmerUffe StolborgPer PfeifferMichael Bau MortensenClaus FristrupSönke Detlefsen

Published in: Journal of clinical pathology (2019)

PB-AC was the most frequent histological subtype of AC. Maspin and IMP3 were the IHC tumour markers with the highest sensitivity. Adenocarcinoma subtypes differed regarding several genetic alterations, whose predictive value remains to be evaluated.

Keyphrases

heavy metals
squamous cell carcinoma
high grade
genome wide
single cell
copy number
locally advanced
radiation therapy
risk assessment
dna methylation
rectal cancer