Poly(lactic-co-glycolic acid) nanomaterial-based treatment options for pain management: a review.
Thuỳ Linh PhạmDong Woon KimPublished in: Nanomedicine (London, England) (2020)
Neuropathic pain is one of the most intense types of chronic pain; it constitutes a pervasive complaint throughout the public health system. With few effective treatments, it remains a significant challenge. Commercially available drugs for neuropathic pain are still limited and have disappointing efficacy. Therefore, chronic neuropathic pain imposes a tremendous burden on patients' quality of life. Recently, the introduction and application of nanotechnology in multiple fields has accelerated the development of new drugs. This review highlights the application of poly(lactic-co-glycolic acid) nanomaterial-based vehicles for drug delivery and how they improve the therapeutic outcomes for neuropathic pain treatment. Finally, future developments for pain research and effective management are presented.
Keyphrases
- neuropathic pain
- pain management
- chronic pain
- spinal cord
- spinal cord injury
- drug delivery
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- healthcare
- prognostic factors
- peritoneal dialysis
- mental health
- type diabetes
- emergency department
- patient reported outcomes
- drug induced
- risk factors
- drug release