Synthesis, in vitro characterization, and anti-tumor effects of novel polystyrene-poly(amide-ether-ester-imide) co-polymeric micelles for delivery of docetaxel in breast cancer in Balb/C mice.

Jaleh VarshosazSaeede EnteshariFarshid HassanzadehBatool Hashemi-BeniMohsen MinaiyanRazieh Mirsafaei

Published in: Drug development and industrial pharmacy (2018)

The results show that the SMA-PAEEI-PEG micelles of DTX could potentially provide a suitable parenteral formulation with more stability, higher cytotoxicity, and improved antitumor activity.

Keyphrases

drug delivery
drug release
cancer therapy
ionic liquid
high fat diet induced
locally advanced
type diabetes
squamous cell carcinoma
radiation therapy
breast cancer risk