L-proline transporter inhibitor (LQFM215) promotes neuroprotection in ischemic stroke.
Gustavo Almeida CarvalhoRaphaela Almeida ChiareliBruno Lemes MarquesRicardo Cambraia ParreiraEric de Souza GilFlávio Silva de CarvalhoAndré Luís Batista da RochaRafaela Ribeiro SilvaFrançois NoëlBoniek Gontijo VazLuciano Morais LiãoShabir AhmadHugo VerliRicardo MenegattiMauro Cunha Xavier PintoPublished in: Pharmacological reports : PR (2023)
This dataset suggests that the new compounds inhibit cerebral L-proline uptake and that LQFM215 promotes neuroprotection and neuro-repair in the acute ischemic stroke model.