High interobserver variability and frequent overdiagnosis of dysplasia in fundic gland polyps can be improved by detecting atypia on the surface epithelium and an abrupt transition to non-neoplastic cells.
Christine E OrrDebra BeneckJose JessurunLihui QinKathrin TyryshkinRhonda K YantissYao-Tseng ChenPublished in: Histopathology (2021)
There is high interobserver variability and a tendency to overdiagnose LGD in FGPs. Strict criteria requiring both surface atypia and abrupt transition for LGD in FGPs result in low interobserver variability.