Tfh cells with NLRP3 inflammasome activation are essential for high-affinity antibody generation, germinal centre formation and autoimmunity.
Zhenhuan ZhaoBihua XuShuang WangMianjing ZhouYuefang HuangChaohuan GuoMengyuan LiJijun ZhaoSun-Sang J SungFelicia GaskinNiansheng YangShu-Man FuPublished in: Annals of the rheumatic diseases (2022)
Tfh population is essential for optimal humoral responses, GC formation and autoimmunity.