Longitudinal Screening Detects Cognitive Stability and Behavioral Deterioration in ALS Patients.

Susan WoolleyRay GoetzPam Factor-LitvakJennifer MurphyJonathan HupfDiana C GarofaloCatherine Lomen-HoerthHoward AndrewsDaragh HeitzmanRichard BedlackJonathan KatzRichard BarohnEric SorensonBjorn OskarssonAmerico Fernandes FilhoEdward KasarskisTahseen MozaffarSharon NationsAndrea SwensonAgnes Koczon-JaremkoGeorgia ChristodoulouHiroshi Mitsumoto

Published in: Behavioural neurology (2018)

We did not detect cognitive change. Behavioral change was detected, and increased disinhibition was found among patients with abnormal baseline behavioral scores. Disinhibition changes did not correlate with disease duration or progression. Baseline behavioral problems were associated with advanced, rapidly progressive disease and study attrition.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
multiple sclerosis
mental health
patient reported outcomes
patient reported