The G-Protein-Coupled Estrogen Receptor Agonist Prevents Cardiac Lipid Accumulation by Stimulating Cardiac Peroxisome Proliferator-Activated Receptor α: A Preclinical Study in Ovariectomized-Diabetic Rat Model.
Faezeh JafarynezhadMohammad ShahbazianZeinab FarhadiMaryam YadeghariMohammad Ebrahim RezvaniFatemeh SafariHossein AzizianPublished in: International journal of endocrinology and metabolism (2022)
G1 as a selective GPER-agonist affects lipid metabolism in T2DM animals. It also plays a vital role in improving cardiac metabolism during postmenopausal diabetic conditions.