Potential of quantitative SEPT9 and SHOX2 methylation in plasmatic circulating cell-free DNA as auxiliary staging parameter in colorectal cancer: a prospective observational cohort study.

Julia BergheimAlexander SemaanHeidrun GevenslebenSusanne GroeningAndreas KnoblichJörn DietrichJulia WeberJörg C KalffFriedrich BootzGlen KristiansenDimo Dietrich

Published in: British journal of cancer (2018)

DNA methylation analysis in plasma is a powerful pre and post-therapeutic diagnostic tool for CRC and may add valuable information to current TNM staging, thereby holding the potential to assist in the development of individually tailored treatment protocols.

Keyphrases

dna methylation
lymph node
genome wide
gene expression
human health
high resolution
healthcare
social media
combination therapy
risk assessment
replacement therapy