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Performance evaluation of Baermann techniques: The quest for developing a microscopy reference standard for the diagnosis of Strongyloides stercoralis.

Woynshet Gelaye YalewNana Aba WilliamsStella KephaAugusto Messa JuniorPedro Emanuel FleitasHelena Martí-SolerDestaw DamtieSissay MenkirAlejandro Javier KrolewieckiLisette Van LieshoutWendemagegn Enbialenull null
Published in: PLoS neglected tropical diseases (2021)
Our results suggest the superior performance of MBCI. It is relatively easy to implement, simple to perform and comparatively cheaper. The CB is by far the commonly used method in routine diagnostic although this technique significantly underestimates the true burden of the disease and thereby contributing to the exclusion of S. stercoralis from the control strategies. Therefore, MBCI is recommended as a routine microscopy-based diagnostic test for S. stercoralis infection, particularly in settings where molecular procedures are not available.
Keyphrases
  • single molecule
  • high resolution
  • clinical practice
  • high speed
  • optical coherence tomography
  • high throughput
  • label free