Systematic review and meta-analysis of augmentation and combination treatments for early-stage treatment-resistant depression.

Fraser ScottElliot HampseySam GnanapragasamBen CarterLindsey Marwood Rachael Wallis TaylorCansu EmreLora KorotkovaJonatan Martín-DombrowskiAnthony J CleareAllan H YoungRebecca Strawbridge

Published in: Journal of psychopharmacology (Oxford, England) (2022)

Our findings support cautious optimism for several augmentation strategies; although considering the high prevalence of TRD, evidence remains inadequate for each treatment option.

Keyphrases

early stage
soft tissue
depressive symptoms
sleep quality
squamous cell carcinoma
combination therapy
radiation therapy
rectal cancer