Clinical significance of soluble programmed cell death-1 and soluble programmed cell death-ligand 1 in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy.
Tetsuro TominagaTakashi AkiyoshiNoriko YamamotoSenzo TaguchiSeiichi MoriToshiya NagasakiYosuke FukunagaMasashi UenoPublished in: PloS one (2019)
Significant increase of sPD-L1 levels after CRT suggests that anti-PD-L1 therapy might be a potential treatment strategy in combination with CRT in advanced rectal cancer.