Gut microbiota-derived metabolites and risk of coronary artery disease: a prospective study among US men and women.

Gang LiuA Heather Eliassen Yanping Li Yang HuAdrian A FrankeLiming LiangFrank B HuAndrew T ChanKenneth J MukamalEric B RimmQi Sun

Published in: The American journal of clinical nutrition (2021)

Our results show that a profile characterized by high enterolactone and low TMAO concentrations in plasma is linked to a healthful dietary pattern and significantly associated with a lower risk of CAD. Overall, these data suggest that, compared with individual markers, multiple microbiota-derived metabolites may facilitate better differentiation of CAD risk and characterization of the relations between diet, microbiota, and CAD risk.

Keyphrases

coronary artery disease
percutaneous coronary intervention
ms ms
cardiovascular events
coronary artery bypass grafting
physical activity
weight loss
electronic health record
machine learning
heart failure
type diabetes
big data
deep learning
left ventricular
aortic valve
artificial intelligence