Virologic outcomes with tenofovir-lamivudine-dolutegravir in adults failing PI-based second-line ART.

Ying Zhao Jacqueline Voget Isaac Singini Zaayid Omar Vanessa Mudaly Andrew Boulle Gary Maartens Graeme Meintjes

Published in: Southern African journal of HIV medicine (2024)

Amongst patients failing second-line PI with no PI resistance, switching to TLD was associated with higher virologic suppression, likely due to improved adherence. Virologic outcomes were similar in patients with PI resistance switched to darunavir-based regimens or TLD.

Keyphrases

antiretroviral therapy
hiv infected patients
hiv infected
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
adipose tissue
insulin resistance
weight loss