Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation.

Ran YanJie RenJing WenZheng CaoDi WuMeng QinDuo XuRoxanne CastilloFeifei LiFang WangZhihua GanChaoyong LiuPing WeiYunfeng Lu

Published in: Advanced materials (Deerfield Beach, Fla.) (2021)

Ischemia-reperfusion injury (IRI) remains as a critical challenge for organ transplantation. Herein, an enzyme therapeutic based on superoxide dismutase and catalase for effective mitigation of IRI and pathogen-induced liver injury is reported, providing a therapeutic for organ transplantation and other diseases.

Keyphrases

ischemia reperfusion injury
cell therapy
climate change

hydrogen peroxide
bone marrow
mesenchymal stem cells

cerebral ischemia
candida albicans

subarachnoid hemorrhage
percutaneous coronary intervention