Class 1, 2, and 3 BRAF-Mutated Metastatic Colorectal Cancer: A Detailed Clinical, Pathologic, and Molecular Characterization.
Marta SchirripaPaola BiasonSara LonardiNicoletta PellaMaria Simona PinoFederica UrbanoCarlotta AntoniottiChiara CremoliniSalvatore CoralloFilippo PietrantonioFabio GelsominoStefano CascinuArmando OrlandiGiada MunariUmberto MalapelleSerena SaggioGabriella FontaniniMassimo RuggeClaudia MescoliStefano LazziLuca Reggiani BonettiGiovanni LanzaAngelo Paolo Dei TosGiovanna De MaglioMaurizio MartiniFrancesca BergamoVittorina ZagonelFotios LoupakisAngelo Paolo Dei TosPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
For the first time, different clinical and pathologic features and outcome data were reported according to the three BRAF mutation classes in mCRC. Specific targeted treatment strategies should be identified in the near future for such patients.