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The role of the tumor microenvironment in colorectal cancer and the potential therapeutic approaches.

Narges ZafariFatemeh KhosraviZahra RezaeeSahar EsfandyariMohamad BahiraeiAfshin BahramyGordon A FernsAmir Avan
Published in: Journal of clinical laboratory analysis (2022)
The present review emphasizes the structure and function of the TME, alterations in the TME, its role in the incidence and progression of CRC, the effects on tumor development and metastasis, and also the potential of its alterations as therapeutic targets. It should be noted that providing novel studies in this field of research might help us to achieve practical therapeutic strategies based on their interaction.
Keyphrases
  • case control
  • human health
  • risk assessment
  • climate change