Lymph node-targeted neoantigen nanovaccines potentiate anti-tumor immune responses of post-surgical melanoma.

Yanhong ChuLingyu QianYaohua KeXiaoyu FengXinjie ChenFangcen LiuLixia YuLianru ZhangYaping TaoRui XuJia WeiBaorui LiuQin Liu

Published in: Journal of nanobiotechnology (2022)

We developed a general vaccine strategy, triggering specific T cell responses, and provided feasible combination strategies for better anti-tumor efficacy.

Keyphrases

lymph node
immune response
neoadjuvant chemotherapy
cancer therapy
sentinel lymph node
toll like receptor
dendritic cells
skin cancer
inflammatory response