FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling.
Mohammad AbohassanMesfer Al ShahraniMohammad Y AlshahraniNaseem BegumSuresh RadhakrishnanPrasanna RajagopalanPublished in: Pharmacological reports : PR (2021)
FNF-12 was able to control the inflammatory responses in in vitro and in vivo asthma models, which may be driven by controlling M2-related Th2 cytokines via MAPK and NF-kB signaling.