Niclosamide Modulates the Cellular and Humoral Immune Response in Balb/c Mice.

Bilal Mahmood Beg Aqeel Javeed Muhammad Ashraf Arfan Ahmad Adeel Sattar Mehmood Ahmad

Published in: Iranian journal of immunology : IJI (2023)

Niclosamide exerts potent immunomodulatory effects by significantly suppressing cell-mediated and humoral immune responses and increasing the levels of TGF-β1 in mice. Niclosamide might be added as an adjuvant to immunosuppressive drugs for the treatment of autoimmune diseases.

Keyphrases

immune response
high fat diet induced
dendritic cells
toll like receptor
single cell
signaling pathway
transforming growth factor
stem cells
metabolic syndrome