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In vivo nuclear RNA structurome reveals RNA-structure regulation of mRNA processing in plants.

Zhenshan LiuQi LiuXiaofei YangYueying ZhangMatthew NorrisXiaoxi ChenJitender CheemaHuakun ZhangYiliang Ding
Published in: Genome biology (2021)
We successfully identify pre-mRNA structure features associated with splicing and polyadenylation at whole-genome scale and validate an RNA structure feature which can regulate splicing. Our study unveils a new RNA structure regulatory mechanism for mRNA processing.
Keyphrases
  • nucleic acid
  • binding protein
  • machine learning
  • transcription factor
  • deep learning