In Vitro Evaluation of P-gp-Mediated Drug-Drug Interactions Using the RPTEC/TERT1 Human Renal Cell Model.

Sonia SaïbSophie HodinValérie BinEdouard OllierXavier Delavenne

Published in: European journal of drug metabolism and pharmacokinetics (2021)

Taken together, the data demonstrate the feasibility of the application of the RPTEC/TERT1 model for evaluating the P-gp inhibitory potentials of drugs and consequently predicting renal drug interactions.

Keyphrases

endothelial cells
cell therapy
emergency department
big data
stem cells
machine learning
induced pluripotent stem cells
artificial intelligence