Genetic susceptibility to acute viral bronchiolitis.

Anu PasanenMinna K KarjalainenMatti KorppiMikko HallmanMika Rämetnull null

Published in: The Journal of infectious diseases (2024)

Our results suggest that genetic variants in CDHR3 and GSDMB modulate susceptibility to bronchiolitis, especially when caused by viruses other than RSV. Severe bronchiolitis in infancy may trigger the development of asthma in genetically susceptible individuals, or it could be a marker of genetic predisposition to asthma.

Keyphrases

respiratory syncytial virus
chronic obstructive pulmonary disease
lung function
genome wide

allergic rhinitis
liver failure
drug induced

copy number
sars cov
respiratory failure

early onset
weight gain
intensive care unit