Sacral nerve stimulation improves colonic inflammation mediated by autonomic-inflammatory cytokine mechanism in rats.

Jie Guo Haifeng JinZhaohong ShiJieyun YinTrisha PasrichaJiande D Z Chen

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)

SNS presents similar anti-inflammatory effects as VNS by inhibiting pro-inflammatory cytokines and increasing anti-inflammatory cytokines via the autonomic pathway. Similar to VNS, SNS may also have a therapeutic potential for colonic inflammation.

Keyphrases

oxidative stress
heart rate variability
heart rate
ulcerative colitis
signaling pathway
blood pressure