SKA1 regulates actin cytoskeleton remodelling via activating Cdc42 and influences the migration of pancreatic ductal adenocarcinoma cells.

Tong LiXu LiuBin XuWei WuYi ZangJuanjuan LiLumin WeiYuting QianHui XuMingping XieQi WangLifu Wang

Published in: Cell proliferation (2020)

This study revealed novel roles for SKA1 as an important regulator of actin cytoskeleton organization and an oncogene in PDAC cells, which may provide insights into developing novel therapeutics.

Keyphrases

induced apoptosis
cell cycle arrest
signaling pathway
small molecule
transcription factor
oxidative stress
cell cycle
single cell
cell proliferation