Impact of Diabetes Mellitus on the Immunity of Tuberculosis Patients: A Retrospective, Cross-Sectional Study.
Ruda WeiPengchuan LiYong XueYinping LiuWen-Ping GongWeiguo ZhaoPublished in: Risk management and healthcare policy (2022)
Hyperglycemia is a risk factor for pulmonary cavity formation and lobe lesions in patients with TB-DM and suppresses the absolute counts of total T lymphocytes, CD8+ T lymphocytes, and NK cells in patients with TB-DM. The potential mechanism may involve the downregulation of innate and adaptive immune responses.
Keyphrases
- immune response
- nk cells
- mycobacterium tuberculosis
- end stage renal disease
- signaling pathway
- newly diagnosed
- ejection fraction
- chronic kidney disease
- glycemic control
- pulmonary hypertension
- prognostic factors
- type diabetes
- peritoneal dialysis
- emergency department
- risk assessment
- toll like receptor
- adipose tissue
- patient reported outcomes
- human health
- oxidative stress
- inflammatory response
- pulmonary tuberculosis
- climate change
- patient reported