Transcriptome analysis reveals synergistic modulation of E-cadherin/N-cadherin in hMSC aggregates chondrogenesis.

Xueping WangYan ZhangJun Yang

Published in: Genes & genomics (2023)

To the best of our knowledge, our study is the first to reveal that the synergistic modulation of E/N-cadherin enhances the chondrogenic differentiation of hMSCs via the ERK1/2-p53 signaling axis.

Keyphrases

healthcare
cancer therapy
mesenchymal stem cells
signaling pathway
cell proliferation
cell adhesion
genome wide
single cell
gene expression