Effect of Mast Cell Chymase on Activation, Proliferation and Transdifferentiation of Hepatic Stellate Cells.

Mingshi YinLongren Wu

Published in: Hepato-gastroenterology (2016)

MC chymase can promote the activation, proliferation and transdifferentiation of HSCs, and plays an important role in occurrence and development of liver fibrosis.

Keyphrases

liver fibrosis
signaling pathway
induced apoptosis
cell cycle arrest
risk assessment
cell death
pi k akt