This study identified the essential genes and pathways associated with exercise and monocytes. Among these, four essential genes (TNF, DUSP1, CXCR4, and NR4A1) and the FoxO signaling pathway play vital roles in the immune function of monocytes. High-intensity exercise may improve the resistance of chronic inflammatory diseases by regulating the expression of these genes.
Keyphrases
- high intensity
- signaling pathway
- bioinformatics analysis
- resistance training
- genome wide
- pi k akt
- genome wide identification
- dendritic cells
- endothelial cells
- peripheral blood
- rheumatoid arthritis
- oxidative stress
- epithelial mesenchymal transition
- genome wide analysis
- dna methylation
- induced apoptosis
- physical activity
- body composition
- long non coding rna
- drug induced