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An in vitro study on the biocompatibility of fibroblasts in sterile and non-sterile low-cost and commercial meshes.

Reiko WiessnerA GehringT KleberN EkwelleR LorenzD-U Richter
Published in: Hernia : the journal of hernias and abdominal wall surgery (2019)
Again, our studies show no significant differences in biocompatibility of fibroblasts between expensive and low-cost meshes. In addition, we detected fibroblast growth even in sterile meshes, independent of the mesh group. To our knowledge, the present study is the first of its kind in terms of qualitative equivalence of sterile and non-sterile in vitro mesh samples. We do not wish to create future patient studies with non-sterilized meshes saturated with antibiotics/antimycotics. However, perhaps we can prove in future studies that under semi-sterile conditions with certain LCMs, wound infection rates can be acceptable.
Keyphrases
  • low cost
  • case control
  • healthcare
  • current status
  • systematic review
  • extracellular matrix
  • case report