Long-Term Health Outcomes of Huntington Disease and the Impact of Future Disease-Modifying Treatments: A Decision-Modeling Analysis.

Gregory F Guzauskas Sarah J Tabrizi Jeffrey D LongAstri ArnesenJamie L Hamilton Daniel O Claassen Lorraine R MunetsiShahid MalikAubri M Kottek Talaha M AliFrank Zhang

Published in: Neurology. Clinical practice (2024)

Our novel HD-modeling framework estimates HD progression over a lifetime and the associated costs and QALYs. Our approach can be used for future cost-effectiveness models as positive DMT clinical trial evidence becomes available.

Keyphrases

clinical trial
current status
open label
study protocol
double blind
decision making