A systematic review of how missing data are handled and reported in multi-database pharmacoepidemiologic studies.

Nicholas B Hunt Helga GardarsdottirMarloes T BazelierOlaf H KlungelRomin Pajouheshnia

Published in: Pharmacoepidemiology and drug safety (2021)

Just over half of the recent pharmacoepidemiologic MDBS reported missing data and two-thirds of these studies reported how they accounted for it. We should increase our vigilance for database completeness in MDBS by reporting and addressing the missing data that could introduce bias.

Keyphrases

electronic health record
adverse drug
big data
case control
emergency department
machine learning
artificial intelligence