The interaction effect of angiogenesis and endothelial dysfunction-related gene variants increases the susceptibility of recurrent pregnancy loss.
E A TrifonovaMaria SwarovskayaO A GanzhaO V VoronkovaT V GabidulinaV A StepanovPublished in: Journal of assisted reproduction and genetics (2019)
The results showed that gene-gene interactions are important for RPL susceptibility. Additionally, analysis of the genotype combinations of several allelic variants provides more information on RPL risk than analysis of independent polymorphic markers.