Agreement between Phenotypically Detected Linezolid Resistance and Mutations in rrl and rplC Genes of Mycobacterium tuberculosis Isolates Using Nanopore Sequencing.
Senjuti SenguptaParul JainRashmi RatnamBhoopendra Kumar PandeyUrmila SinghVijay KumarAshutosh PaliwalParul JainPublished in: International journal of mycobacteriology (2024)
This study revealed a considerable discrepancy between phenotypic and genotypic detection of LZD resistance in MTB. Further research is needed to better understand the genetic mechanisms underlying LZD resistance and to develop reliable molecular diagnostics for rapid resistance detection.